Chai Discovery

Biotech · San Francisco, US

Biotech using computational models to predict and reprogram biochemical interactions for faster drug discovery.

Founders

Joshua Meier (United States · ♂) — Helped build ESM1, the first transformer protein-language model at Facebook, then worked at Absci and OpenAI before founding Chai Discovery to generate novel proteins and antibodies with AI.
Jack Dent (United States · ♂) — Met Meier on the first day of CS classes at Harvard and built product and engineering teams at Stripe before co-founding Chai Discovery as President.
Matthew McPartlon (United States · ♂) — A machine-learning researcher who co-founded Chai Discovery to build foundation models for molecular interactions.
Jacques Boitreaud (France · ♂) — A computational biology researcher who co-founded Chai Discovery to apply AI to protein and antibody design.

Shares the most investors with (number = shared investors):

Date	Round	Amount
Dec 2025	Funding round Chai Discovery raised $130 million at a $1.3 billion valuation, with Oak HC/FT, General Catalyst, Thrive, Menlo and OpenAI, bringing the total to $225 million for its AI molecular design suite.	$130M
Aug 2025	Series A Chai Discovery closed a $70 million Series A led by Menlo Ventures through the Anthology Fund with Anthropic, to accelerate the development of therapies via computational models.	$70M

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